Objective Sensitized genetic screen to identify new components of the Wingless signaling pathway in Drosophila The role of the wingless protein in cell patterning in both the Drosophila embryo and imaginal discs has recently received a great deal of attention. However, while some of the components of the pathway by which the Wingless signal is transduced have been identified, (armadillo, dishevelled and shaggylzeste-white 3) most have not been recovered by classical genetic screens. Using wing margin patterning as an assay for Wg function, I propose to conduct a screen for mutations that decrease or increase the effectiveness of signaling by the Wg protein. Such an approach should allow me to identify new component of the pathway and therefore gain insight about the role of Wg in Drosophila development. Fields of science natural sciencesbiological sciencesbiochemistrybiomoleculesproteinsnatural sciencesbiological sciencesgeneticsmutationmedical and health sciencesclinical medicineembryology Programme(s) FP4-TMR - Specific research and technological development programme in the field of the training and mobility of researchers, 1994-1998 Topic(s) 0302 - Post-doctoral research training grants TL06 - Developmental Biology Call for proposal Data not available Funding Scheme RGI - Research grants (individual fellowships) Coordinator EUROPEAN MOLECULAR BIOLOGY LABORATORY EU contribution No data Address Meyerhofstrasse 1 HEIDELBERG Germany See on map Total cost No data Participants (1) Sort alphabetically Sort by EU Contribution Expand all Collapse all Not available France EU contribution No data Address See on map Total cost No data
