Objective
Sensitized genetic screen to identify new components of the Wingless signaling pathway in Drosophila
The role of the wingless protein in cell patterning in both the Drosophila embryo and imaginal discs has recently received a great deal of attention. However, while some of the components of the pathway by which the Wingless signal is transduced have been identified, (armadillo, dishevelled and shaggylzeste-white 3) most have not been recovered by classical genetic screens. Using wing margin patterning as an assay for Wg function, I propose to conduct a screen for mutations that decrease or increase the effectiveness of signaling by the Wg protein. Such an approach should allow me to identify new component of the pathway and therefore gain insight about the role of Wg in Drosophila development.
Fields of science (EuroSciVoc)
Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
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Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
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Funding Scheme
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Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
HEIDELBERG
Germany
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