Analysis of the nod factor signal transduction cascade. Effects of inositolphospholipids on change of the cytoskeleton

Project Information

Grant agreement ID: FMBI960824

Project closed

Start date 5 September 1996

End date 4 September 1998

Funded under

• Specific research and technological development programme in the field of the training and mobility of researchers, 1994-1998

Total cost No data

EU contribution No data

Coordinated by

WAGENINGEN UNIVERSITY
Netherlands

Objective

The Rhizobium-legume symbiosis is set in motion by a signal exchange between plant and bacterium. The bacterial production of the so-call Nod factors play an essential role by triggering several plant responses like root hairs deformation, the formation of nodule primordia and the induction of several transcriptional-regulated plant genes. However, the signal transduction pathway leading to plant response is unknown. As it was mentioned, Nod factors induces root hairs deformation and this event is visible within 1 h of the induction. Although calcium ion and phosphoinositides have been suggested to play a rolet further studies are necessary to establish the transducer and second messenger involved in the transduction pathway. Firstly, by using a confocal microscope linked to a microinje(tion equipment we will be able to follow the Nod factors responses by measuring the effect of microinjected drugs in root hairs deformation. We will be focused on the inositolphospholipid signaling following preliminary studies on the metabolism of the precursor phospholipids. Secondly, by using a cell biology approach, we will study the involvement of phosphinositides in the actin cytoskeleton changing.

Fields of science (EuroSciVoc)

CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques.

• natural sciences › biological sciences › microbiology › bacteriology
• natural sciences › chemical sciences › inorganic chemistry › alkaline earth metals
• natural sciences › biological sciences › cell biology
• natural sciences › biological sciences › biological behavioural sciences › ethology › biological interactions
• natural sciences › physical sciences › optics › microscopy › confocal microscopy

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Programme(s)

• FP4-TMR - Specific research and technological development programme in the field of the training and mobility of researchers, 1994-1998

Topic(s)

• 0302 - Post-doctoral research training grants
• TL05 - Cell Biology

Call for proposal

Data not available

Funding Scheme

RGI - Research grants (individual fellowships)

Coordinator

WAGENINGEN UNIVERSITY

• EU contribution: No data
• Address: 3,Dreijenlaan 3 ; 6703 HA WAGENINGEN ; Netherlands
• Total cost: No data

Participants (1)

Not available

Spain

• EU contribution: No data
• Total cost: No data