Objective Research objectives and content We propose to synthesize dendrimers which will be able to specifically recognize anions usign redox sensors located at the termini of the dendrimer branches. This recognition should strongly depend on the core, on the length of the dendritic segment added at each generation and on the number of dendritic generations. In order to investigate this point, several generations of dendrimers will be synthe size, functionnalized with redox centers, and tested for the recognition of the a nions. We should be able to investigate the best dendrimer for each anion in or der to recognize and optimize this process. The recognition of the anion with the dendrimer will be effected using an amido metallocene/amidometallocenium termini using the electrostatic interaction betwe en its cationic oxidized form and the anion in synergy with the supramolecular interaction between the acidic hydrogenation of the amide function and the anion The interaction should be an order of magnitude larger with the cationic metallocenium termini than with neutral metallocene form. This should be probed by monitoring the shift of the NH chemical shift in lH NMR when switching from an 18-electron cationic cobalticenium to the isoelectronic (18 electron) neutral ferrocene. Thus both lH NMR and electrochemical methods will be used in complementarity for anionic recognition, which will enrich the set of possibilities of sensors. The topology, surface, shape and cavities of dendrimers provide the potential for the function of drug transport and delivery to biological targets. To reach this ambitious goal, it is fires importance achieve SPECIFIC MOLECULAR RECOGNITION of molecular fragments and ions by dendrimers Molecular rectifiers, transistors and photodiodes have envisaged, the later requiring features such as those of charge-transfer states in organic molecules, in metal complexes. The general objectives of this postdoctoral project offer exciting perspectives in the BIOTECHNOLOGY AND TECHNOLOGY FIELDS. Fields of science natural scienceschemical scienceselectrochemistrynatural sciencesmathematicspure mathematicstopologyengineering and technologyelectrical engineering, electronic engineering, information engineeringelectronic engineeringsensors Programme(s) FP4-TMR - Specific research and technological development programme in the field of the training and mobility of researchers, 1994-1998 Topic(s) 0302 - Post-doctoral research training grants TC07 - Molecular Aspects of New Materials Call for proposal Data not available Funding Scheme RGI - Research grants (individual fellowships) Coordinator Centre National de la Recherche Scientifique (CNRS) Address 351 cours de la libération 33405 Talence France See on map EU contribution € 0,00 Participants (1) Sort alphabetically Sort by EU Contribution Expand all Collapse all Not available Spain EU contribution € 0,00 Address See on map
