Synthesis of several generations of dendrimers with amidometallocene/ amidometallocenium termini with various topologies and study as spectroscopyand electrochemical sensors

Información del proyecto

Identificador del acuerdo de subvención: FMBI961651

Proyecto cerrado

Fecha de inicio 1 Junio 1997

Fecha de finalización 31 Mayo 1999

Financiado con arreglo a

• Specific research and technological development programme in the field of the training and mobility of researchers, 1994-1998

Coste total € 0,00

Aportación de la UE Sin datos

Coordinado por

Centre National de la Recherche Scientifique (CNRS)
France

Objetivo

Research objectives and content
We propose to synthesize dendrimers which will be able to specifically recognize anions usign redox sensors located at the termini of the dendrimer branches. This recognition should strongly depend on the core, on the length of the dendritic segment added at each generation and on the number of dendritic generations. In order to investigate this point, several generations of dendrimers will be synthe size, functionnalized with redox centers, and tested for the recognition of the a nions. We should be able to investigate the best dendrimer for each anion in or der to recognize and optimize this process.
The recognition of the anion with the dendrimer will be effected using an amido metallocene/amidometallocenium termini using the electrostatic interaction betwe en its cationic oxidized form and the anion in synergy with the supramolecular interaction between the acidic hydrogenation of the amide function and the anion The interaction should be an order of magnitude larger with the cationic metallocenium termini than with neutral metallocene form.
This should be probed by monitoring the shift of the NH chemical shift in lH NMR when switching from an 18-electron cationic cobalticenium to the isoelectronic (18 electron) neutral ferrocene. Thus both lH NMR and electrochemical methods will be used in complementarity for anionic recognition, which will enrich the set of possibilities of sensors. The topology, surface, shape and cavities of dendrimers provide the potential for the function of drug transport and delivery to biological targets. To reach this ambitious goal, it is fires importance achieve SPECIFIC MOLECULAR RECOGNITION of molecular fragments and ions by dendrimers
Molecular rectifiers, transistors and photodiodes have envisaged, the later requiring features such as those of charge-transfer states in organic molecules, in metal complexes. The general objectives of this postdoctoral project offer exciting perspectives in the BIOTECHNOLOGY AND TECHNOLOGY FIELDS.

Ámbito científico

• natural sciences › chemical sciences › electrochemistry
• natural sciences › mathematics › pure mathematics › topology
• engineering and technology › electrical engineering, electronic engineering, information engineering › electronic engineering › sensors

Programa(s)

• FP4-TMR - Specific research and technological development programme in the field of the training and mobility of researchers, 1994-1998

Tema(s)

• 0302 - Post-doctoral research training grants
• TC07 - Molecular Aspects of New Materials

Convocatoria de propuestas

Data not available

Régimen de financiación

RGI - Research grants (individual fellowships)

Coordinador

Centre National de la Recherche Scientifique (CNRS)

• Aportación de la UE: Sin datos
• Dirección: 351 cours de la Libération ; 33405 Talence ; Francia
• Coste total: Sin datos

Participantes (1)

Not available

España

• Aportación de la UE: Sin datos
• Coste total: Sin datos