Synthesis of the antitumour macrolide spongistatin 1

Project Information

Grant agreement ID: FMBI972451

Project closed

Start date 1 April 1998

End date 31 March 2000

Funded under

• Specific research and technological development programme in the field of the training and mobility of researchers, 1994-1998

Total cost € 0,00

EU contribution No data

Coordinated by

University of Cambridge
United Kingdom

Objective

Research objectives and content
The aim of this project is the exploration of new synthetic routes which would lead to the total synthesis of the important | antimitotic agent spongistatin 1. In the course of this work several synthetic methodologies, mainly chiral aldol reactions, already developed at the host research group would be applied. In addition, there would be a need for the development of new . methods which would be also suitable for a general application in Organic Synthesis. The objective of this project could be extended towards the preparation of synthetic analogues of the natural product in order to test their biological and pharmacological activities. Training content (objective, benefit and expected impact)
The fulfilment of this project would improve the research training received by the applicant during his Ph.D. period in the field of Organic Synthesis, and would be useful for a future work in EU Universities or industries.
Links with industry / industrial relevance (22)

Programme(s)

• FP4-TMR - Specific research and technological development programme in the field of the training and mobility of researchers, 1994-1998

Topic(s)

• 0302 - Post-doctoral research training grants
• TC01 - Synthesis, New Molecules and Methods

Call for proposal

Data not available

Funding Scheme

RGI - Research grants (individual fellowships)

Coordinator

University of Cambridge

• EU contribution: No data
• Address: Lensfield Road ; CB2 1EW Cambridge ; United Kingdom
• Total cost: No data

Participants (1)

Not available

Spain

• EU contribution: No data
• Total cost: No data