Objective
Research objectives and content
The main objective of this research project is the functional analysis of the RNase H and zinc-finger motifs located in the 3' region of I-factor-like elements. These domains, as well as the termination mode are characteristic of this subgroup of elements and are not included in the present model of transposition of LINEs. The activity of these domains has not even been tested. As a second objective, I would like to test the hypothesis that I-factor-like elements are retrotranscribed in the cytoplasm. The project will consist on the establishment of a suitable in vitro transposition system for the I-factorlike element in the laboratory of Dr. Bucheton and then, with Dr. Finnegan, the analysis of how specific mutations affect the transposition capability of the element. Training content (objective, benefit and expected impact)
This research project will be acquainted me with completely new techniques on molecular biology like cell culture, making and handling of gene constructs and perhaps protein expression and its analysis. The knowledge or this technology can be useful not only for this project but to analyse any gene. Working or two different research groups, I will benefit from the training ability of both laboratories as well as a specialised supervision on each part of the investigation.
Links with industry / industrial relevance (22)
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- natural sciences biological sciences biochemistry biomolecules proteins
- natural sciences biological sciences genetics mutation
- natural sciences mathematics pure mathematics mathematical analysis functional analysis
- natural sciences biological sciences molecular biology
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Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
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Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
91198 GIF SUR YVETTE
France
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.