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Content archived on 2024-04-30

Design and synthesis of new electroluminescent metal complexes for improved disease diagnosis

Objective



Research objectives and content
The aim of the project is to design and synthesise new metal complexes with high sensitivity in electrochemiluminescence detection. A new class of metal complexes with high emission quantum yield and different redox properties will be synthesised choosing appropriate substituents and varying the metal ion. The new compounds will be investigated with electrochemical methods and in electrochemiluminescence. Then, appropriate molecules will be made available with reactive functional groups (labels) for conjugation to biomolecules (Proteins, peptides, nucleic acids, haptens). The conjugates will be further evaluated as substitutes in routine assay, e.g. HIV, progesterone, DNA analysis.
Training content (objective, benefit and expected impact)
The proposed project will train the candidate in organic synthesis, electrochemical and biochemical methods and applications in immunoassays and DNA testing. This research will have a lot of impact on the carrer prospects of the candidate, broadening her knowledge in different topies, acquiring new skills and industrial experience.
Links with industry / industrial relevance (22)
The project would be carried out in the research laboratories of an industry and would investigate new systems and improve products already in the market.

Fields of science (EuroSciVoc)

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Call for proposal

Data not available

Coordinator

Böhringer Mannheim GmbH
EU contribution
No data
Address
9-15,Bahnhofstrasse
82327 Tutzing
Germany

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Total cost
No data