Silicone cross-linked polyurethane materials for thrombus and biodegradation resistant small-diameter vascular grafts and coating of blood contacting devices

Objective

The objective of the project is to synthesize new functional silicone based materials (SILCROTHANE) with very low thrombogenecity activity and optimal biostability, and to process the new material by proprietary processing technologies to fabricate the following pre-clinical devices:
- a medium-diameter SILCROTHANE coated Dacron vascular grafts,
- a SILCROTHANE coated, stainless-steel 316L, balloon expandable vascular stent,
- a small-diameter vascular grafts made entirely of the SILCROTHANE material.

Programme(s)

• FP5-GROWTH - Programme for research technological development and demonstration on "Competitive and sustainable growth 1998-2002"

Topic(s)

• 1.1.3.-5. - RTD Activities of a Generic Nature : materials and their technologies for production and transformation and new and improved materials and production technologies in the steel field

Funding Scheme

CSC - Cost-sharing contracts

Coordinator

NATIONAL RESEARCH COUNCIL OF ITALY

Address

Piazzale Aldo Moro 7
00185 Roma
Italy

Participants (5)

ANGIOLOGICA B.M. SRL

Italy

Address

Via Giovanni Xxiii 7
27028 San Martino Siccomario

INVESTIGACION Y DESARROLO DE EQUIPOS MEDICOS S.A.

Spain

Address

Pol. Industrial 'Nicomedes Garcia'
40140 Valverde De Majano

PROVINCIA ITALIANA DELLA CONGREGAZIONE DEI FIGLI DELLA IMMACOLATA CONCEZIONE

Italy

Address

Via Dei Monti Di Creta 104
00167 Roma

THE UNIVERSITY OF LIVERPOOL

United Kingdom

Address

Daulby Street Royal Liverpool University Hospital
L69 3GA Liverpool

UNIVERSITY OF ALCALA

Spain

Address

33,6,Ctra N-ii 33,6 Campus Universitario
28871 Alcala De Henares