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Silicone cross-linked polyurethane materials for thrombus and biodegradation resistant small-diameter vascular grafts and coating of blood contacting devices

Objective

The objective of the project is to synthesize new functional silicone based materials (SILCROTHANE) with very low thrombogenecity activity and optimal biostability, and to process the new material by proprietary processing technologies to fabricate the following pre-clinical devices:
- a medium-diameter SILCROTHANE coated Dacron vascular grafts,
- a SILCROTHANE coated, stainless-steel 316L, balloon expandable vascular stent,
- a small-diameter vascular grafts made entirely of the SILCROTHANE material.

Funding Scheme

CSC - Cost-sharing contracts

Coordinator

NATIONAL RESEARCH COUNCIL OF ITALY
Address
Piazzale Aldo Moro 7
00185 Roma
Italy

Participants (5)

ANGIOLOGICA B.M. SRL
Italy
Address
Via Giovanni Xxiii 7
27028 San Martino Siccomario
INVESTIGACION Y DESARROLO DE EQUIPOS MEDICOS S.A.
Spain
Address
Pol. Industrial 'Nicomedes Garcia'
40140 Valverde De Majano
PROVINCIA ITALIANA DELLA CONGREGAZIONE DEI FIGLI DELLA IMMACOLATA CONCEZIONE
Italy
Address
Via Dei Monti Di Creta 104
00167 Roma
THE UNIVERSITY OF LIVERPOOL
United Kingdom
Address
Daulby Street Royal Liverpool University Hospital
L69 3GA Liverpool
UNIVERSITY OF ALCALA
Spain
Address
33,6,Ctra N-ii 33,6 Campus Universitario
28871 Alcala De Henares