Objective
This project aims at launching an entirely new concept for development of new biomaterials for medical use. We aim at developing techniques for biosynthesis of large quantities of spider silk protein, which will be modified and refined and used as a raw material for the production of orthopedic devices. The genes for silk protein will be cloned and expressed in different systems. The expressed proteins will be characterised with respect to structure, biocompatibility and biomechanical properties When the final product has been achieved it will be used to produce orthopaedic devices as
(i) external fixators and casts as well as
(ii) internal fixators as pins, screws and plates.
In a second phase spider protein implants, as bone grafts, ligaments and tendons will be developed. All products will be subjected to animal trials prior to clinical testing.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques.
- medical and health sciencesclinical medicinesurgery
- natural sciencesbiological sciencesbiochemistrybiomoleculesproteins
- medical and health sciencesclinical medicineorthopaedics
- engineering and technologyindustrial biotechnologybiomaterials
- medical and health sciencesmedical biotechnologyimplants
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Call for proposal
Data not availableFunding Scheme
CSC - Cost-sharing contractsCoordinator
750 07 UPPSALA
Sweden