Objective
The European Collaborative Interspecific Backcross (EUCIB) is a major collaborative European effort to provide resources for the high resolution genetic mapping of the mouse, an important model organism in the Human Genome project. A 1,000 animal backcross has been anchor mapped across the genome providing DNAs to allow users to map new markers to a resolution of 0.3cM. EUCIB is also supported by a sophisticated database. In addition, in collaboration with the Mouse Genome Center in the US, EUCIB is being used for the construction of a high resolution genetic map of 6,000 microsatellites across the mouse genome - a prelude to the STS (sequence tagged site) based YAC contiging of the mouse genome. EUCIB aims to map 3,000 of the proposed 6,000 microsatellites. This proposal requests support to help Europe to take a major proactive role in the provision of YAC clones covering a major portion of the mapped microsatellites and thus contribute in a substantial way to the construction of the mouse physical map. Two mouse YAC libraries have been constructed in Europe and are being widely and successfully used. We propose to screen both these libraries for 1,750 genetically mapped microsatellites over the next three years laying down YACs that will cover up to one-third of the mouse genome. The proposal involves four centres - the Pasteur Institute, Paris, France; Genethon, France.St. Mary's Hospital Medical School, London, UK and the Medical Research Council Human Genome Mapping Resource Centre, UK. We also request funding to help with the database support of the project and database links with complementary efforts at the US Mouse Genome Center.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- natural sciences computer and information sciences databases
- natural sciences biological sciences genetics DNA
- natural sciences biological sciences genetics genomes
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Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
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Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
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Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
W2 1PG London
United Kingdom
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.