Objective
Various dietary factors may play an important role in the process of carcinogenesis. Several epidemiologic data demonstrate an association of foods or nutrients with the prevention of cancer. Breast cancer is the most frequent malignancy among women in Western countries, with in increasing incidence. In western Europe 1 out of 9 women develop breast cancer, in contrast to Mediterranean countries where the incidence is significantly lower. In Asian populations the incidence of breast and endometrial cancer, the most common gynaecological tumour, is even lower. Genetical factors have been excluded, since populations that migrate from low to high incidence countries develop breast cancer rates that approximate those in the new host country. AS a Greek student in Germany I am especially interested in the prevention of tumor development by dietary components, especially on the impact of Mediterranean diet in carinogenesis. Mediterranean diet contains severe! nutrients, i.e olive oil and phytoestrogens, which have recently been suggested 10 have chemopreventive effects against breast and endometrial cancer. Therefore, a major aim is to find substances for the prevention of cancer which could be of major interest in western European countries, We have focused on testing nutritional compounds in human cells in-vitro to facilitate new insights in chemo-prevention for future investigations. Tamoxifen and endometrium: Tamoxifen has being used in the adjuvant therapy of breast cancer patients for almost twenty years with a significant improvement in both recurrence-free and overall survival. Tamoxifen could play a major role in the chemoprevention of breast cancer. A significant correlation between tamoxifen use and the development of endometrial carcinomas was demonstrated, although the precise incidence of tamoxifen-associated endometrial pathological changes is still not clear. The mechanism of tamoxifen-induced endometrial carcinogenesis is thought to be due to an estrog
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- medical and health sciences clinical medicine oncology breast cancer
- medical and health sciences health sciences nutrition
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Programme(s)
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Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
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Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
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Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Funding Scheme
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Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
30 823 KRAKOW
Poland
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.