Sixth International Symposium on Biologically Reactive Intermediates
The Sixth International Symposium on Biologically Reactive Intermediates (BRI VI) is the sixth of a suite of quinquenal meetings which study the impact of biologically reactive intermediates of drugs and xenobiotics on biological systems and on human health. The preceeding ones happened in Turku (Finland, H. Vainio 1975) Guilford (UK, GG Gibson 1980), College park (USA, G Nelson 1985), Tucson (USA, Glen Sipes, 1990), Munich,(FRG, H. Greim 1995). Each of these metings allowed confrontation of recent advances in this stimulating field. The new one will be hold in PARIS and is dedicated to Pr Sten Orrenius of the Karolinska Institute as guest of Honnor. The scientific programm is wide with 10 sessions of each 4 or 5 speakers.
The title of each session are:
1) Covalent Binding of reactive intermediates to proteins;
2)Covalent Binding of reactive intermediates to DNA;
3) Structure-activity relationships;
4) Chemistry of specific biologically reactive metabolites;
5) Reactive oxygen species as biologically reactive metabolites;
6) Nitic oxide/ peroxynitrite;
7) Biologically reactive metabolites induced DNA damage and repair;
8) Tissue-specific response to biologically reactive metabolites;
9) Impact of biologically reactive metabolites on human health;
10) Chemoprotection and interindividual differences in response to biologically reactive metabolites.