Exploitation of dt40 cells to study the mechanism of immunoglobulin gene diversification

Project Information

SILVESTRO CONTICELLO

Grant agreement ID: HPMF-CT-2002-02085

Project closed

Start date 1 October 2002

End date 30 September 2004

Funded under

• Programme for research, technological development and demonstration on "Improving the human research potential and the socio-economic knowledge base" (1998-2002)

Total cost € 114 272,00

EU contribution € 114 272,00

Coordinated by

MEDICAL RESEARCH COUNCIL
United Kingdom

Objective

We will use the DT40 cell line to investigate the role of immunoglobulin specific transcription factors in targeting of hyper mutation, the mechanism of action of AID in controlling the process and the possible involvement of error prone polymerases.

Fields of science (EuroSciVoc)

CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques.

• natural sciences › biological sciences › genetics › mutation

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Programme(s)

• FP5-HUMAN POTENTIAL - Programme for research, technological development and demonstration on "Improving the human research potential and the socio-economic knowledge base" (1998-2002)

Topic(s)

Data not available

Call for proposal

Data not available

Funding Scheme

RGI - Research grants (individual fellowships)

Coordinator

MEDICAL RESEARCH COUNCIL

• EU contribution: No data
• Address: Hills Road ; CB2 2QH CAMBRIDGE ; United Kingdom
• Total cost: No data