Objective
Within this project research will be performed at KREATECH Biotechnology B.V ., at the Department of Molecular Cell Biology of the Leiden University Medical Center (LUMC), and at the Department of Applied Physics of the Delft University of Technology (TU Delft). All laboratories are (scientifically) highly skilled, modem, and with state-of-the-art equipment. KREATECH is a biotechnology industrial organization with patents on the Universal Linkage System (ULS^R) and Mycobacterium diagnostics (ABC). KREATECH has broad knowledge of the biochemical and biological properties of ULS^R and on the development and production of biochemicals and diagnostical based on these patents. LUMC is highly skilled and experienced (amongst others) in the in-vitro (molecular) detection of biomolecules and (more recently) in the development of micro array technology. The TU Delft is highly skilled and experienced (amongst others) in the development of (nano-litre scale) biosensor technology. All institutes are (inter)nationally highly acknowledged and have extended (scientific) networks, both national and international. Moreover, all institutes have vast experience in guiding and teaching fellows at all scientific levels. In this project research is proposed to significantly increase diagnostic assay sensitivity up to a factor of 100.000 (10^5), both for nucleic acids and proteins. This problem will be tackled at:
1) the level of the detection format,
1a) by miniaturization ('from ELISA/dot blot- via micro array- to biosensor format'), and
1b) by optimization of biomolecule - ULS^R- solid support binding, and
2) the level of sample processing (by a direct ULS^R 'target labeling' technology).
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- engineering and technology electrical engineering, electronic engineering, information engineering electronic engineering sensors biosensors
- natural sciences biological sciences biochemistry biomolecules nucleic acids
- natural sciences biological sciences biochemistry biomolecules proteins
- natural sciences biological sciences cell biology
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Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
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Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
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Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
1032 LG AMSTERDAM
Netherlands
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.