Objective
The Marie-Curie fellows will learn through research at KREATECH Biotechnology BV, at the Department of Pharmacokinetics and Drug Delivery (PK&DD) of the University of Groningen, and at the Leiden Institute for Chemistry (LIC) of the Leiden University in The Netherlands. The Department of PK&DD is highly skilled and experienced in the development of targeted drugs and in in-vitro and in-vivo testing of these drugs. The LIC is highly skilled and experienced in (in)organic combinatorial chemistry. All laboratories are modern and with state-of-the-art equipment. All institutes are (inter) nationally highly acknowledged and have extended (scientific) networks, both national and international. Moreover, all institutes have broad experience in guiding and teaching fellows at all scientific levels. KREATECH is a biotechnology industrial organization with patents on the Universal Linkage System (ULS^(R)) and Mycobacterium diagnostics (ABC). KREATECH has broad knowledge of the biochemical and biological properties of ULS^(R) and on the development and production of biochemicals and diagnostical based on these patents.In this project, ULS^(R) will be applied in the design of targeted drugs. The problem of cell-specific drug delivery will be tackled through biochemical and biomedical research at two fronts:
1) the linkage of small chemical drugs that cannot be linked to homing devices by conventional chemistry, and
2) the linkage of bio-active therapeutic peptides to carrier proteins through a drug-releasing bond (release at target site). The developed drug prototypes will be tested both in-vitro and in-vivo.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- natural sciences biological sciences biochemistry biomolecules proteins
- medical and health sciences basic medicine pharmacology and pharmacy pharmacokinetics
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Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
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Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
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Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
1032 LG AMSTERDAM
Netherlands
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.