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Isolation and structure of biologically active secondary metabolites


PHD FELLOWSHIPS IN ORGANIC CHEMISTRY. A number of 3-12 month positions for doctoral students are available at the Department of Chemistry of Natural Products, University of Napoli "Federico II" in the subject of "Biologically Active Secondary Metabolites From Marine Organisms". The project is directed to the isolation, structure determination, and examination of biological activity of organic compounds from marine organisms collected all over the world. The research group at the University of Napoli is a world leader in the study of marine natural products, being directed by Prof. Ernesto Fattorusso, one of the pioneers of the chemistry of the sea, who has been working for over 30 years in this field. The staff of the Training Site has full access to all the instruments (two NMR spectrometers and three mass spectrometers) owned by the "Interdepartmental Research Center of Instrumental Analysis' of the University of Napoli. The fellow will be involved in the entire research process: extraction of the organisms, chromatographic isolation of pure compounds, structure elucidation mainly on the basis of spectral data, and preliminary examination of the biological activity, but the training will be focused on structure determination. At the end of the training, the fellow should be able to extract structural information on a organic molecule from appropriately chosen experiments. Candidates may not be Italian nationals, must be nationals of a Member or Associated State of the EU, or have resided in Member States for the five years, and should be 35 years old or less. Candidates should be following a Ph.D. program in organic chemistry, phytochemistry, pharmaceutical chemistry, or related subjects, preferably with a background in NMR and/or mass spectroscopy. Candidates should also be fluent in English (or in Italian). The Training Site strongly supports and will implement the Equal Opportunities Policies (in particular between women and men) of the EC.


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Via D.Montesano 49
80131 NAPOLI

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