Objective
Position available for doctoral fellows in the fields of genomics and marker development in filamentous fungi. The following topics can be addressed:
(i) Contribution to the analysis of genome organization of L. maculans. Following characterization of L. maculans or heterologous EST s (including candidate genes from other fungal species) , search for functional clustering by hybridization on the SAC library. Genome location of these clusters in the physical map and chromosomes separated by PFGE. Relationship with the location of known genes of L. maculans, including A VR genes.
(ii) Comparison with the genome organization of related pathogenic fungi, by analyzing the occurrence, or not, of similar stretches of OAFs upon the availability of similar material and tools in the fellow host lab.
(iii) Use of mini satellites as tools for population genetics or epidemiology in L. maculans or related fungal species. The availability of numerous sequence data in L. maculans, or cloning strategies targeted at markers linked in repulsion enabled us to design strategies to generate minisatellites. These single-locus sequences are common in fungal genomes and have the main advantage over microsatellites that they may be easily separated and analyzed using regular agarose electrophoresis due to the differences in size from one repeat to the other. New minisatellites will be characterized and their usefulness as markers assessed on natural L. maculans populations. Similar strategies can be developed on related fungal species as in (ii).
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- medical and health sciences health sciences public health epidemiology
- natural sciences biological sciences microbiology mycology
- natural sciences chemical sciences electrochemistry electrophoresis
- natural sciences biological sciences genetics chromosomes
- natural sciences biological sciences genetics genomes
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Programme(s)
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Multi-annual funding programmes that define the EU’s priorities for research and innovation.
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Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
78026 VERSAILLES
France
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