Objective Description:The Research Infrastructure PCDD at Biomedical Primate Research Centre (BPRC) is located in Rijswijk, The Netherlands and provides a unique possibility to investigate pathogenic mechanisms and new therapies for chronic and degenerative disease in non-human primate disease models. The centre has pedigreed breeding colonies of genetically characterised New World monkeys (common marmosets and cotton-top tamarins) and Old World monkeys (rhesus macaques) for biomedical research. The facility provides visiting researchers the necessary scientific and technical support for the experiments plus the usage of specialised laboratories and animal housing and care infrastructure. Studies of the kind undertaken in the infrastructure provide insight in genetic and immunological mechanisms operating in transplant rejection and chronic inflammatory diseases, such as rheumatoid arthritis, multiple sclerosis and inflammatory bowel disease.Application:The research of the BPRC has immediate relevance in the field of therapy development. The permanent aim of the research group is to improve the existing models where necessary, for example by the implementation of clinically relevant diagnostic tools. Via basic research into the critical pathogenic mechanisms operating in the models is potential targets for more effective and safer therapy are sought. The vast knowledge on primate genetics and immunology present in the institute can form the basis for development of new disease models.Project Manager:Dr. Margreet JonkerImmunobiology DepartmentBiomedical Primate Research CentreLange Kleiweg 139, RIJSWIJK, Postbus 3306, 2280 GH á RIJSWIJK, The NetherlandsTel: +31-15-2842687Fax: +31-15-2843999Email: jonker@bprc.nl Fields of science natural sciencesbiological scienceszoologymammalogyprimatologymedical and health sciencesclinical medicinerheumatologymedical and health scienceshealth sciencesinflammatory diseasesmedical and health sciencesclinical medicinegastroenterologyinflammatory bowel diseasemedical and health sciencesbasic medicineneurologymultiple sclerosis Programme(s) FP5-HUMAN POTENTIAL - Programme for research, technological development and demonstration on "Improving the human research potential and the socio-economic knowledge base" (1998-2002) Topic(s) 1.4.1.-2. - Access to Research Infrastructures Call for proposal Data not available Funding Scheme LFC - Access to Research Infrastructures Coordinator FOUNDATION BIOMEDICAL PRIMATE RESEARCH CENTRE EU contribution No data Address 151,Lange Kleiweg 139 2288 GJ RIJSWIJK ZH Netherlands See on map Total cost No data
