The mechanism, specificity and inhibition of enzymes belonging to the xanthine oxidase family : medical and industrial applications

Objective

Eight young post-doctoral scientists will be trained in the following advanced techniques; enzymology; x-ray crystallographic macromolecular structure solution; transient and steady-stake kinetics; bio-organic and bio-inorganic chemistry; fungal, bacterial, and mammalian genetics; protein purification and over expression systems; molecular modeling of compounds with site-specific molecular interactions with enzymes; continuous wave and pulsed multifrequency EPR and ENDOR .The training will take place in eight well-founded, internationally -recognized laboratories in five EU countries. The young researchers will generally receive training in at least two network laboratories and will make short visits to others. Other young researchers from network laboratories will make short visits to different participants for exchange of information and materials. Involvements in network and local seminar programmes will be encouraged as will short visits to the associated industrial laboratories.

Programme(s)

• FP5-HUMAN POTENTIAL - Programme for research, technological development and demonstration on "Improving the human research potential and the socio-economic knowledge base" (1998-2002)

Funding Scheme

NET - Research network contracts

Coordinator

JOHN INNES CENTRE

Address

Norwich Research Park, Colney
Norwich
United Kingdom

Participants (7)

FUNDACAO DA FACULDADE DE CIENCIAS E TECNOLOGIA DA UNIVESIDADE NOVA DE LISBOA

Portugal

Address

Quinta Da Torre
2825 Monte Da Caparica

MARIO NEGRI INSTITUTE FOR PHARMACOLOGICAL RESEARCH

Italy

Address

Via Eritrea 62
20157 Milano

MAX-PLANCK-GESELLSCHAFT ZUR FOERDERUNG DER WISSENSCHAFTEN E.V.

Germany

Address

Am Klopferspitz 18 A
82152 Martinsried

SAARLAND UNIVERSITY

Germany

Address

Klinikium Bau 76
66041 Saarbruecken

UNIVERSITE DE PARIS-SUD XI

France

Address

Rue Georges Clemenceau 15, Bftiment 400
91405 Gometz La Ville

UNIVERSITY OF SUSSEX

United Kingdom

Address

Falmer
BN1 9QG Brighton

WESTFAELISCHE WILHELMS - UNIVERSITAET MUENSTER

Germany

Address

Corrensstrasse, 3
48149 Muenster