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The mechanism, specificity and inhibition of enzymes belonging to the xanthine oxidase family : medical and industrial applications

Objective

Eight young post-doctoral scientists will be trained in the following advanced techniques; enzymology; x-ray crystallographic macromolecular structure solution; transient and steady-stake kinetics; bio-organic and bio-inorganic chemistry; fungal, bacterial, and mammalian genetics; protein purification and over expression systems; molecular modeling of compounds with site-specific molecular interactions with enzymes; continuous wave and pulsed multifrequency EPR and ENDOR .The training will take place in eight well-founded, internationally -recognized laboratories in five EU countries. The young researchers will generally receive training in at least two network laboratories and will make short visits to others. Other young researchers from network laboratories will make short visits to different participants for exchange of information and materials. Involvements in network and local seminar programmes will be encouraged as will short visits to the associated industrial laboratories.

Coordinator

JOHN INNES CENTRE
Address
Norwich Research Park, Colney
Norwich
United Kingdom

Participants (7)

FUNDACAO DA FACULDADE DE CIENCIAS E TECNOLOGIA DA UNIVESIDADE NOVA DE LISBOA
Portugal
Address
Quinta Da Torre
2825 Monte Da Caparica
MARIO NEGRI INSTITUTE FOR PHARMACOLOGICAL RESEARCH
Italy
Address
Via Eritrea 62
20157 Milano
MAX-PLANCK-GESELLSCHAFT ZUR FOERDERUNG DER WISSENSCHAFTEN E.V.
Germany
Address
Am Klopferspitz 18 A
82152 Martinsried
SAARLAND UNIVERSITY
Germany
Address
Klinikium Bau 76
66041 Saarbruecken
UNIVERSITE DE PARIS-SUD XI
France
Address
Rue Georges Clemenceau 15, Bftiment 400
91405 Gometz La Ville
UNIVERSITY OF SUSSEX
United Kingdom
Address
Falmer
BN1 9QG Brighton
WESTFAELISCHE WILHELMS - UNIVERSITAET MUENSTER
Germany
Address
Corrensstrasse, 3
48149 Muenster