Objective
Foreseen Results
The results will consist of estimates of the risk of lung cancer in CCE/NIS by occupational medicine, air pollution and tobacco smoking.
The objectives of the projects are to identify occupational risk factors of lung cancer in Countries of Central Europe (CCE) and new Independent States (NIS), to quantify the contribution of occupational factors to the lung cancer burden.
The project will consist of an epidemiological case-control study, with data collection via personal interview and collection of blood and lung tissue samples. All incident cases of lung cancer in the selected areas or hospitals will be included. Controls will be selected among hospital patients undergoing minor surgical operations in the same hospitals as the cases. A detailed interview of each case and each control will be conduced either in the hospital or at home to elicit information on exposure to occupational agents and to other major known and suspected risk factors of lung cancer : tobacco smoking, passive smoking, dietary habits, residential history (to assess exposure to air pollution), family history of cancer, and personal history of X-rays and of diseases. Information on the clinical aspects of the neoplasms will be collected for cases only. Specific questionnaires will be used to elicit detailed information on job tasks and agents used in the case of employment in industries entailing exposure to known and suspected lung carcinogens. The study will be conducted in 6 areas from CCE/NIS characterized by high prevalence of industrialization.
The preliminary list of agents for which exposure will be assessed includes asbestos, arsenic, chromium, nickel, polycyclic aromatic hydrocarbons, formaldehyde, strong inorganic acids, man-made mineral fibers, wood dust, dust, gas and solvents.
No special measurements of air pollution will be made for this study, but existing data will be used to classify the current and historical exposures pertaining to the current and previous places of residence of each case and control.
Exposure to known and suspected occupational carcinogens will be assessed via an evaluation of the questionnaire responses by a team of experts (typically an industrial hygienist, chemist and occupational physician) set up in each participating center. This involves assessing level, probably duration of exposure to each agent, together with the confidence in the assessment, for each period of employment of each case and control.
Fields of science (EuroSciVoc)
- humanities history and archaeology history
- medical and health sciences clinical medicine oncology lung cancer
- natural sciences chemical sciences inorganic chemistry transition metals
- engineering and technology environmental engineering air pollution engineering
- natural sciences earth and related environmental sciences environmental sciences pollution
Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Data not available
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
69372 LYON
France
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.