Objective
* Implementation of rapid, simple and cheap diagnostic tests for measles that can be used under field conditions.
* Establishment of a diagnostic virological lab, operating according to WHO standards. This lab may participate in WHO eradication efforts for measles in the near future.
* Evaluation of the epidemiology of measles in the Sudan, including vaccine coverage and efficacy.
* Insight in the overall health impact of measles in the Sudan, including estimation of case-fatality ratios.
* Evaluation of naturally acquired and vaccine-induced measles virus-specific antibody and T-cell mediated immunity.
* Knowledge about the mechanisms of measles-induced immunosuppression.
Expected Outcome
* Technology transfer from WHO reference labs to the Sudan, including the building of an infrastructure and training of personnel, which will be essential in the planned WHO global eradication program for measles.
* Knowledge about epidemiology and health impact of measles in the Sudan.
Field work
* Establishment and follow-up of a cohort for the measurement of maternal antibodies, the estimation of the true incidence of measles and the performance of the new diagnostic field test.
* Establishment of a cohort of acute measles cases for immunological and virological studies.
Lab work
After training in Rotterdam and Lyon, immunological and virological studies will be continued in the Institute of Endemic Diseases in Khartoum, in which a new virology lab will be established.
Training
A MD student (epidemiological work, diagnostic test and a PhD student (immunological and virological studies) from the Sudan will be trained in this project.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- natural sciences biological sciences microbiology virology
- medical and health sciences health sciences public health epidemiology
- medical and health sciences basic medicine pharmacology and pharmacy pharmaceutical drugs vaccines
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Programme(s)
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Multi-annual funding programmes that define the EU’s priorities for research and innovation.
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Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
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Funding Scheme
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Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
3015 GE ROTTERDAM
Netherlands
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.