CORDIS fournit des liens vers les livrables publics et les publications des projets HORIZON.
Les liens vers les livrables et les publications des projets du 7e PC, ainsi que les liens vers certains types de résultats spécifiques tels que les jeux de données et les logiciels, sont récupérés dynamiquement sur OpenAIRE .
Résultats exploitables
A principally new generation of base antisense oligonucleotides was developed which are able to cause the death of certain selected micro-organisms and particularly also of mollicutes.
For this purpose oligonucleotides were developed which are complementary
(i) to ribosome promotor sites of DNA, and
(ii) to "signature" rRNA sequences.
These are the highly conserved sequence in mollicutes.
In addition, the same effect was obtained by blocking the function of "signature" rRNA sequences by oligodeoxynucletides complementary to these "signature" sequences. This is principally a new approach applicable to control growth of micro-organisms. In addition, these oligonucleotides interact with ribosomal operons on the genomic DNA (only one to two of these operons are present in mycoplasmas) and attach to double-stranded DNA, forming its three-stranded structure triplex at this site.
In the course of the project, furthermore, new superspecific antisense oligonucleotides have been developed.
Recherche de données OpenAIRE...
Une erreur s’est produite lors de la recherche de données OpenAIRE
Aucun résultat disponible