Objective
It is well recognized that hypertension is associated with important remodelling of the vascular system. The pharmacological and physiological properties of vessels also change with hypertension, yet previous studies of changing vascular responsiveness with hypertension have been characterized by conflicting results. Recent advances in cell signalling have shown that factors which modulate vascular tone (neurotransmitters, hormones, stretch), and growth factors utilise similar intracellular calcium messengers and mechanisms.
The main goal of this project is, therefore, to study the influence of hypertension on smooth muscle cell calcium handling, and to throw light on the mechanisms involved in the development and the maintenance of hypertension. Pharmacological, electrophysiological and biochemical approaches will be combined for studying calcium handling, according to the resources and interests of each team. The aim is to establish normalised conditions for studying the change in the responsiveness and the properties of vessels in hypertensive disease.
Fields of science (EuroSciVoc)
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Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
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Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
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Coordinator
1200 Bruxelles
Belgium
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.