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Contenido archivado el 2024-04-16

CANCER TREATMENT WITH LIGHT IONS BEAM IN EUROPE

Objetivo

The goal of EULIMA is to study the implementation of a hospital based, dedicated light-ion medical facility in Europe in order to make the benefits of light ions available to a large number of cancer patients.
%This objective is in agreement with the European Community strategy: improvement of local treatments of cancer.
The physical and radiobiological characteristics of high energy particle beams as well as the available clinical experience indicate that irradiation of certain tumour types or sites with these beams will improve local control (at present, about 40% of the patients with only localized disease at the time of diagnosis are not cured).

The concerted action has studied the feasibility of a hospital based light ion accelerator facility for the treatment of a large number of cancer patients. In a first part, the socioeconomic aspects, including clinical indications, patient numbers, the operational organization of a large light ion therapy centre, treatment cost and comparison with the actual cost of conventional treatment, have been addressed. In the second part, detailed studies (including cost) of the technical infrastructure have been carried out: design of a superconducting cyclotron, a synchrotron, beam transport and beam splitting, raster and spot scanning beam delivery systems and a variable incidence gantry have been made. Experiments to evaluate radiobiological properties of certain particle types, different beam delivery systems and the use of radioactive accelerated particles for quality control have been undertaken.

The study indicates that up to 3000 patients per year could be treated at 1 light ion accelerator facility at a treatment cost that should not exceed by more than a factor of 2 the cost of comparable conventional radiotherapy.
The feasibility study includes four parts:

1. The accelerator: the aim of this study is to evaluate options based on a superconducting cyclotron or a synchrotron. Considering various elements of the feasibility study and given the foreseeable development of technology, the Project Management Group has opted, after consultation of independent experts, for the synchrotron option.

2. The beam delivery system: two strategies for delivering the dose in the tumour volume, raster scanning or spot (pixel) scanning have been studied. A variable incidence angle system (gantry) has been investigated.

3. An experimental programme including:

- measurements of radio biological properties of carbon, oxygen and neon ions;
- the study of different magnetic beam scanning strategies;
- the production of radioactive ion beams.

4. Socio-economic and clinical aspects: clinical indications and their incidence have been determined and the factors allowing to evaluate the treatment costs in Europe have been analysed.

Ámbito científico (EuroSciVoc)

CORDIS clasifica los proyectos con EuroSciVoc, una taxonomía plurilingüe de ámbitos científicos, mediante un proceso semiautomático basado en técnicas de procesamiento del lenguaje natural. Véas: El vocabulario científico europeo..

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Coordinador

Laboratoire du Cyclotron
Aportación de la UE
Sin datos
Dirección
227 avenue de la Lanterne
06200 Nice
Francia

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Coste total

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