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Content archived on 2024-05-27

Fundamental mechanisms of apoptosis/cell death regulation in normal and cancer cells.

Objective

The general objective of this program is to understand the principal mechanisms governing apoptosis or programmed cell depth, both in normal cells and in cancer cells, to unravel differences in physiology and pathology of cell death regulation, and to design novel strategies for the correction of disease-associated imbalances in cell death regulation. In particular, we are interested in understanding how cancer cells become apoptosis resistant and how this resistance can be overcome. A consortium of 11 leading research teams from 7 different countries will identify and characterize novel cell death inducing or cell death inhibitory pathways via a multidisciplinary approach integrating advanced technologies of Molecular and Cellular Biology. In addition, the group will monitor cancer cells for alterations in such cell death modulator pathways, and manipulate them to kill chemotherapy-resistant tumour cells.

Fields of science (EuroSciVoc)

CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.

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Topic(s)

Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.

Call for proposal

Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.

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Funding Scheme

Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.

CSC - Cost-sharing contracts

Coordinator

CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
EU contribution
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Address
Rue Guy Môquet 19
94801 Villejuif
France

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Total cost

The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.

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Participants (10)

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