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Optical mammography: imaging and characterisation of breast lesions by pulsed near-infrared laser light

Objective

Breast cancer is the most frequent cause of death of women under 50 years and x-ray mammography suffers from a large number of false positive results. Near-infrared laser pulse mammography is a novel non-invasive imaging technique to improve detection and characterisation of breast cancer, supplementing conventional mammography. Multinational clinical trials will be performed at four European sites on 450patients using improved prototypes of laser-pulse mammographs. For analysis of optical mammograms refined semi-empirical and rigorous mathematical methods will be developed. Through a concerted effort of all clinical and technical partners, scattering and absorption coefficients of normal breast tissue and lesions will be determined to improve the scientific basis of optical mammography. From the results of clinical trials the diagnostic accuracy of laser-pulse mammography will be assessed and compared to conventional mammography techniques.

Funding Scheme

CSC - Cost-sharing contracts

Coordinator

BUNDESREPUBLIK DEUTSCHLAND
Address
100,Bundesallee 100
38023 Braunschweig
Germany

Participants (8)

FOUNDATION OF RESEARCH AND TECHNOLOGY - HELLAS
Greece
Address
Vasilika Vouton
71110 Iraklion
HUMBOLDT-UNIVERSITAET BERLIN
Germany
Address
Unter Den Linden 9
10099 Berlin
LUND UNIVERSITY
Sweden
Address
Professorsgatan 1
221 00 Lund
POLYTECHNIC OF MILAN
Italy
Address
Piazza Leonardo Da Vinci 32
20133 Milano
PROVINCIA LOMBARDO-VENETA ORDINE RELIGIOSO CHIERICI REGOLARI MINISTRI INFERMI (CAMILLIANI)
Italy
Address
Via Francesco Nava 31
20159 Milano
UNIVERSITY COLLEGE LONDON
United Kingdom
Address
Gower Street 5
WC1E 6BT London
UNIVERSITY HOSPITAL ROTTERDAM
Netherlands
Address
40,Dr. Molewaterplein 40
3015 GD Rotterdam
UNIVERSITY OF TWENTE
Netherlands
Address
1,Drienerlolaan 5
7522 NB Enschede