Biological, clinical and genetic markers of future risk of cardiovascular disease

Objective

The project will improve understanding of the relationship between early life factors and cardiovascular disease mortality, morbidity and intermediate risk profile, and identify markers amenable to early intervention and prevention, within the framework of six unique birth cohort studies from England, Finland, Faroes (Denmark) and Greece, including data on 58500 people born since 1920s. This internationally valuable material since pregnancy or birth provides a unique platform for integrating a genetic, clinical and epidemiological approach. We will evaluate the risk over the life course using pre-existing data, data from the analysis of stored blood samples, and data to be collected in this study, and consolidate methods of data collection in order to improve comparability between countries and allow data pooling. A European collaborative group will be established for longitudinal studies and the results will be widely distributed.

Fields of science

• social sciences › sociology › demography › mortality
• medical and health sciences › clinical medicine › obstetrics
• medical and health sciences › clinical medicine › cardiology › cardiovascular diseases

Programme(s)

• FP5-LIFE QUALITY - Specific Programme for research, technological development and demonstration on "Quality of life and management of living resources", 1998-2002

Topic(s)

• 1.1.1.-7. - Chronic and degenerative diseases, cancer, diabetes, cardivascular diseases and rare diseases

Call for proposal

Data not available

Funding Scheme

CSC - Cost-sharing contracts

Coordinator

IMPERIAL COLLEGE OF SCIENCE, TECHNOLOGY AND MEDICINE

Address

South Kensington Campus
London
United Kingdom

Participants (5)

DANISH EPIDEMIOLOGY SCIENCE CENTRE

Denmark

Address

10,artillerivej 5, Building 206
2300 Koepenhagen

Medical Research Council (MRC)

United Kingdom

Address

20 Park Crescent
W1N 4AL London

NATIONAL AND KAPODISTRIAN UNIVERSITY OF ATHENS

Greece

Address

Ag. Thomas Ave 17
11527 Athens

UNIVERSITY OF BRISTOL

United Kingdom

Address

Senate House, Tyndall Avenue
BS8 1TH Bristol, Clifton

UNIVERSITY OF OULU

Finland

Address

Aapistie 1
90220 Oulu