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Biological, clinical and genetic markers of future risk of cardiovascular disease

Objective

The project will improve understanding of the relationship between early life factors and cardiovascular disease mortality, morbidity and intermediate risk profile, and identify markers amenable to early intervention and prevention, within the framework of six unique birth cohort studies from England, Finland, Faroes (Denmark) and Greece, including data on 58500 people born since 1920s. This internationally valuable material since pregnancy or birth provides a unique platform for integrating a genetic, clinical and epidemiological approach. We will evaluate the risk over the life course using pre-existing data, data from the analysis of stored blood samples, and data to be collected in this study, and consolidate methods of data collection in order to improve comparability between countries and allow data pooling. A European collaborative group will be established for longitudinal studies and the results will be widely distributed.

Funding Scheme

CSC - Cost-sharing contracts

Coordinator

IMPERIAL COLLEGE OF SCIENCE, TECHNOLOGY AND MEDICINE
Address
South Kensington Campus
London
United Kingdom

Participants (5)

DANISH EPIDEMIOLOGY SCIENCE CENTRE
Denmark
Address
10,Artillerivej 5, Building 206
2300 Koepenhagen
Medical Research Council (MRC)
United Kingdom
Address
20 Park Crescent
W1N 4AL London
NATIONAL AND KAPODISTRIAN UNIVERSITY OF ATHENS
Greece
Address
Ag. Thomas Ave 17
11527 Athens
UNIVERSITY OF BRISTOL
United Kingdom
Address
Senate House, Tyndall Avenue
BS8 1TH Bristol, Clifton
UNIVERSITY OF OULU
Finland
Address
Aapistie 1
90220 Oulu