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The role of tissue transglutaminase in inducing gluten t cell response and autoantibody formation in coeliac disease

Objetivo

Deamidation and transamidation activities of tTG are measured and the influence of tTG autoantibodies is determined. Gluten-tTG complexes are applied to investigate the role of cognate T/B cell interaction for the formation of tTG autoantibodies. An in vitro marine system, a marine adoptive transfer model and an in vitro human system will be used.

Convocatoria de propuestas

Data not available

Coordinador

THE NATIONAL HOSPITAL UNIVERSITY OF OSLO
Aportación de la UE
Sin datos
Dirección
Pilestredet 32
0027 OSLO
Noruega

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Coste total
Sin datos