Objective
Helicobacter pylori (Hp) infection is an important cause of gastric cancer (GC), duodenal and gastric ulcer, and gastric lymphoma. Factors affecting progression, pathways and outcomes of this process are not known. Vegetables and fruits are associated with GC, but the mechanism of action remains unknown. Role of nutrients, alcohol and tobacco has not been established. Genetic susceptibility may influence individual responses to these factors explaining why only a minority infected persons developed GC. In a multicenter prospective study carried out in nine European countries, a nested case-control study will be conducted aimed to elucidate the individual and joint effects of Hp infection, genetic polymorphisms, nutritional status and environmental factors putatively involved in the aetiology of GC in the European population.
Fields of science
- agricultural sciencesagriculture, forestry, and fisheriesagriculturehorticulturefruit growing
- medical and health sciencesclinical medicineoncology
- agricultural sciencesagriculture, forestry, and fisheriesagriculturehorticulturevegetable growing
- natural scienceschemical sciencesorganic chemistryalcohols
Call for proposal
Data not availableFunding Scheme
CSC - Cost-sharing contractsCoordinator
08907 Hospitalet Del Llobregat
Spain
See on map
Participants (4)
50135 Firenze
See on map
53100 Siena
See on map
69372 Lyon
See on map
CB2 2QQ Cambridge
See on map