Objective
Insulin resistance is a key predictor for the development of type 2 diabetes mellitus and appears to be important in the pathogenesis of cardiovascular disease (CVD), which is the leading cause of morbidity and premature mortality in Europe, although prevalence rates differ between geographical regions. Type 2 diabetes, which enhances the risk of CVD 3- to 5- fold, was estimated by WHO to have a prevalence of 20-25 million in Europe in 1997. The degree of insulin resistance is influenced by multiple factors, including genetic and environmental factors (e.g. obesity and inactivity). This project will use the expertise and organisational infrastructure of an existing European collaborative research group to study 1500 healthy subjects. Baseline measurements will be made of insulin resistance, classical cardiovascular risk factors, glucose tolerance, candidate genotypes and CVD by carotid artery intima-media thickness. Investigations will be repeated after 3 years to define the relation between insulin resistance and the development of CVD and type 2 diabetes. This study will provide unique information on the importance of insulin resistance in the development of CVD and diabetes, and has implications for the development of prevention and treatment strategies relevant to Europe.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- social sciences sociology demography mortality
- medical and health sciences clinical medicine endocrinology diabetes
- medical and health sciences clinical medicine cardiology cardiovascular diseases
- medical and health sciences health sciences nutrition obesity
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Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
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Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
56100 PISA
Italy
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.