Objective
This project intends to provide a mechanism whereby new and promising approaches to the management of Myelofibrosis with Myeloid Metplasia (MMM)can be tested in a systematic and scientific manner. This objective will be the effort of a research network which first goal will be to offer to the scientific community a definition of improvement for MMM that will facilitate the standardization, conduct, interpretation and efficiency of clinical trials and might also be useful to physicians to decide how severe is the disease and if responded adequately to therapy in routine clinical practice. Selection of outcome variables through international surveys, and a combination of statistical and consensus techniques will be the methodologies used. Moreover, as a prototype of future studies, the role of cellular tyrosine kinase pathway in the myeloproliferation and the biological outcomes of a tyrosine kinase inhibitor, STI 571, will be evaluated.
Call for proposal
Data not availableFunding Scheme
CON - Coordination of research actionsCoordinator
27100 Pavia
Italy
Participants (12)
92118 Clichy
16132 Genova
62307 Lens
08036 Barcelona
94800 Villejuif
50924 Koeln
33076 Bordeaux
10000 Zagreb
S10 2JN Sheffield
1090 Wien
25123 Brescia
89070 Ulm