An european network for myelofibrosis consensus on definition of disease improvement and biological impact of new therapies (EUMNET)

Objective

This project intends to provide a mechanism whereby new and promising approaches to the management of Myelofibrosis with Myeloid Metplasia (MMM)can be tested in a systematic and scientific manner. This objective will be the effort of a research network which first goal will be to offer to the scientific community a definition of improvement for MMM that will facilitate the standardization, conduct, interpretation and efficiency of clinical trials and might also be useful to physicians to decide how severe is the disease and if responded adequately to therapy in routine clinical practice. Selection of outcome variables through international surveys, and a combination of statistical and consensus techniques will be the methodologies used. Moreover, as a prototype of future studies, the role of cellular tyrosine kinase pathway in the myeloproliferation and the biological outcomes of a tyrosine kinase inhibitor, STI 571, will be evaluated.

Programme(s)

• FP5-LIFE QUALITY - Specific Programme for research, technological development and demonstration on "Quality of life and management of living resources", 1998-2002

Topic(s)

• 1.1.1.-7. - Chronic and degenerative diseases, cancer, diabetes, cardivascular diseases and rare diseases

Call for proposal

Data not available

Funding Scheme

CON - Coordination of research actions

Coordinator

IRCCS POLICLINICO SAN MATTEO - ISTITUTO DI RICOVERO E CURA A CARATTERE SCIENTIFICO

Address

Viale Golgi 19
27100 Pavia
Italy

 

Participants (12)

AVICENNE UNIVERSITY SCHOOL OF MEDICINE

France

Address

Boulevard General Leclerc
92118 Clichy

 

AZIENDA OSPEDALIERA OSPEDALE SAN MARTINO DI GENOVA E CLINICHE UNIVERSITARIE CONVENZIONATE

Italy

Address

Via Rosanna Benzi, 2
16132 Genova

 

FACULTE LIBRE DE MEDECINE

France

Address

Centre Hospitalier, Route De La Bassee
62307 Lens

 

HOSPITAL CLINIC BARCELONA

Spain

Address

Calle Villaroel 170
08036 Barcelona

 

INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE

France

Address

Avenue Paul Vaillant-couturier 14-16
94800 Villejuif

 

UNIVERSITAET KOELN

Germany

Address

Joseph-stelzmann-strasse 9
50924 Koeln

 

UNIVERSITE VICTOR SEGALEN - BORDEAUX II

France

Address

Leo Saignat 146, Bat. 1A Carreire Nord
33076 Bordeaux

 

UNIVERSITY HOSPITAL MERKUR ZAGREB

Croatia

Address

I. Zajca 19
10000 Zagreb

 

UNIVERSITY OF SHEFFIELD

United Kingdom

Address

Royal Hallamshire Hospital, Glossop Road
S10 2JN Sheffield

 

UNIVERSITY OF VIENNA

Austria

Address

Währinger Gürtel 18-20
1090 Wien

 

UNIVERSITÀ DEGLI STUDI DI BRESCIA

Italy

Address

Piazzale Spedali Civili 1
25123 Brescia

 

University of Ulm

Germany

Address

Albert-einstein-allee 11
89070 Ulm