Objective Heat shock proteins are antigens of immune responses in autoimmunity. In experimental models they suppress inflammation and in clinical trials in diabetes and arthritis hsp60 has a proven therapeutic potential. We propose to analyse the underlying mechanisms by monitoring immunity to hsp60 in the models, in patients and during hsp60 peptide trials, with respect to both the adaptive and the innate part of the immune system. Fields of science medical and health sciencesclinical medicinerheumatologynatural sciencesbiological sciencesbiochemistrybiomoleculesproteinsmedical and health sciencesclinical medicineendocrinologydiabetesmedical and health sciencesbasic medicineimmunology Programme(s) FP5-LIFE QUALITY - Specific Programme for research, technological development and demonstration on "Quality of life and management of living resources", 1998-2002 Topic(s) 1.1.1.-7. - Chronic and degenerative diseases, cancer, diabetes, cardivascular diseases and rare diseases Call for proposal Data not available Funding Scheme CSC - Cost-sharing contracts Coordinator UTRECHT UNIVERSITY Address Yalelaan 1 3584 CL Utrecht Netherlands See on map EU contribution € 0,00 Participants (5) Sort alphabetically Sort by EU Contribution Expand all Collapse all DEUTSCHE DIABETES FORSCHUNGSGESELLSCHAFT E.V. Germany EU contribution € 0,00 Address Auf'm hennekekamp 65 40225 Duesseldorf See on map PEPTOR LTD Israel EU contribution € 0,00 Address Kyriat weizmann, building 16 76326 Rehovot See on map THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE United Kingdom EU contribution € 0,00 Address Hills road addenbrooke's nhs trust 5 CB2 2QQ Cambridge See on map UNIVERSITY MEDICAL CENTRE UTRECHT Netherlands EU contribution € 0,00 Address Lundlaan 6 3584EA Utrecht See on map WEIZMANN INSTITUTE OF SCIENCE Israel EU contribution € 0,00 Address Herzel street 2 76100 Rehovot See on map
