Objective
Monochorionic (MC) twins are rare (3/1,000) but have a much higher risk of perinatal death or neurological sequelae than dichorionic twins or singleton pregnancies. Furthermore, 15 % of MC twin gestations complicate with the Twin-to-twin transfusion syndrome (TTS). The cause for this poorer outcome lies in the ever-present vascular connections in the MC placentas. Although MC status can be identified early in pregnancy, this is often not done due to unawareness of its consequences. There are neither data to offer guidance on how to follow up these high-risk pregnancies, nor how to treat TTS. Clinical studies are proposed to improve pathophysiologic insight, such as the determination of the natural history of early-diagnosed MC twins and the exact risk for developing TTS. We will evaluate the incidence and nature of long-term sequelae in survivors of TTS. A prospective study will be conducted to determine which is the best therapy for TTS, neurological morbidity in survivors being the primary variable. In our study patients we will determine the placental angioarchitecture, correlate it to clinical pregnancy outcome and use this information to establish a computer model for the disease. In addition instrumental innovations are proposed to improve therapy of TTS and abnormal MC twin pregnancy.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
You need to log in or register to use this function
Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
projects.no_data
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
3000 LOUVAIN / LEUVEN
Belgium
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.