Objective
The overall goal of the project involving 12 Partners is to determine if specific genetic changes in lung carcinogenesis are detectable in the respiratory epithelium of individuals who have an increased risk of developing lung cancer. Partners are enrolling 1200 individuals with a very high risk of developing lung cancer i.e. Second Primary Lung Cancers (SPLC) in 12 clinical centres in Europe. The recruited individuals will be followed-up over 3 years, 1-3% per year will develop SPLC (-100 SPLC). Specimens obtained will be 'banked' and assessed for a range of molecular/pathological markers considered to be involved in carcinogenesis. We have tackled the question of early detection on a molecular pathway approach and plan to examine; oncogenic pathways and cell cycle regulation, genetic instability, angiogenic and growth factors, signal pathways, post-transcriptional regulation genomic expression profiling and genotyping.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
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Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
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Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
L3 9AT LIVERPOOL
United Kingdom
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Participants (14)
BT9 7AB BELFAST
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6500 GS NIJMEGEN
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54511 VANDOEUVRE-LES-NANCY
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31008 PAMPLONA
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69120 HEIDELBERG
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38706 LA TRONCHE
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20133 MILANO
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74245 LOWENSTEIN
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15-276 BIALYSTOK
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8 Dublin
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69126 HEIDELBERG
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EH8 9AG EDINBURGH
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LE1 5WW LEICESTER
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1081 HV AMSTERDAM
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