Image guided gene therapy with modified stem cells: local delivery, tracking of labeled cells, and control of expression with local hyperthermia

Objective

Adult stem cells will be transfected and labelled with MRI contrast agents for tracking of the cells towards the target. Transgene expression will be controlled by MRI guided hyperthermia and the heat-sensitive hsp70 promoter.

Fields of science

• medical and health sciences › medical biotechnology › genetic engineering › gene therapy
• medical and health sciences › medical biotechnology › cells technologies › stem cells

Programme(s)

• FP5-LIFE QUALITY - Specific Programme for research, technological development and demonstration on "Quality of life and management of living resources", 1998-2002

Topic(s)

• 1.1.1.-7. - Chronic and degenerative diseases, cancer, diabetes, cardivascular diseases and rare diseases

Call for proposal

Data not available

Funding Scheme

RGI - Research grants (individual fellowships)

Coordinator

UNIVERSITE VICTOR SEGALEN - BORDEAUX II

Address

Rue Léo-saignat 146, Case 93
33076 Bordeaux
France

Links