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Evaluation of selected natural topoisomerase poisons in human cancer cells.

Objective

Evaluation in human cancer cells of non-toxic natural compounds that have show interest as topoisomerase poisons. The active ones will be evaluated in combination with some currently used anticancer drugs to detect a synergism that might be used to decrease their toxicity limiting their usefulness.

Funding Scheme

RGI - Research grants (individual fellowships)

Coordinator

UNIVERSITY OF NEWCASTLE UPON TYNE
Address
Park Terrace 1
NE1 7RU Newcastle Upon Tyne
United Kingdom