Objective
The project aims to address the needs of deaf patients 22.5 individual in the eu. By performing resaerech wich will lead to high quality genetic counselling and the discovery of curative treatements. To fulfil these expectations a number of human deafness will be isolated and moleculare daignastic test associated with a detailed clinicale description of the differnt gene defect will be developed. The major challenge i.e. the development nof new therapies will be tackled direclty as well as by elucuidating the underling dfective patwaays. To achieve this conplementary approaches will be set up and mouse and zebrafisch model for human daefness will be generated witch much effort on the connexin 26 gene defect 50% of congenitale deafness .the role of daefness gene in the susceptibility to environmentale causes of hearing loss .i.e. to noise and aminoglglycosides will be also analysed. Finally the consortium will produce epidemiologicale data on hereditary daefness in the eu.
Call for proposal
Data not availableFunding Scheme
CSC - Cost-sharing contractsCoordinator
75724 PARIS
France