Objective
The pace at which sequence information is generated in various model organisms is rapidly growing. However, the ability to generate genetic information has far outstripped our ability analyse it to the point that it is medically relevant. Clearly, functional genomic analyses might benefit from
1) novel genetic models, whose purpose is to complement existing models to obtain comprehensive genetic data on the functional level; and
2) methodology that can bridge the gap between genotype and phenotype in order to understand gene function in vertebrate organisms. Accordingly, we propose to lay the foundation of using Xenopustropicalis as a vertebrate model system for biomedical research by developing transposable elements as molecular tools for functional genomics. In this project we propose to cover the full spectrum of gene analysis by
1) developing efficient transposable element vectors for the introduction of nucleic acid into frog chromosomes;
2) applying transposon technology to efficiently inactivate and rapidly isolate genes in the amphibian model;
3) applying transpose on technology to express genes in different tissues of the amphibian model in order to establish gene function and involvement of gene products in cellular pathways.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: https://op.europa.eu/en/web/eu-vocabularies/euroscivoc.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: https://op.europa.eu/en/web/eu-vocabularies/euroscivoc.
- natural sciences biological sciences biochemistry biomolecules nucleic acids
- natural sciences biological sciences genetics chromosomes
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Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
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Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
13092 BERLIN
Germany
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.