Objectif
The molecular basis of programmed cell death (PCD ) , a system common to both plants and animals, will be studied to learn more about signal transduction cascades. PCD is a process of cell suicide critical for development and tissue homeostasis of multicellular organisms. It requires sophisticated signal transduction machinery, controlled by an evolutionary conserved program. Understanding PCD is important for drug discovery in human medicine and pathogen resistance in agriculture. Shared features of plant and animal PCD will be used to deduce the primordial components of eukaryotic PCD To increase our understanding in this field, micro spectroscopic techniques will be used because they provide quantitative information on molecular interactions and dynamic events involving signalling molecules (SMD) , they can be used as high throughput methods and combined with other advanced imaging methods.
Champ scientifique
- medical and health sciencesbasic medicinepharmacology and pharmacydrug discovery
- natural sciencesbiological sciencesbiochemistrybiomoleculesproteins
- agricultural sciencesagriculture, forestry, and fisheriesagriculture
- medical and health sciencesbasic medicinephysiologyhomeostasis
- natural sciencesphysical sciencesopticsspectroscopy
Appel à propositions
Data not availableRégime de financement
CSC - Cost-sharing contractsCoordinateur
6700 ES WAGENINGEN
Pays-Bas