Objective
Micro vascular lesions and accelerated arteriosclerosis are the major causes of morbidity and early mortality in diabetic patients. Development of complications is influenced by genetic factors. Identification of the genes in correlation with specific phenotypes will aid a better risk assessment, allow early intervention and the development of new therapeutic approaches. Both excellent clinical and genetic expertise are needed. We propose to combine clinical and genetic data from major European institutions to identify genes involved in diabetic complications. Large patient cohorts will be screened for polymorphisms in candidate genes for association. These studies will be aided through the use of animal models derived for specific phenotypes. The combination of clinic al and human genetic studies on one hand and genetic animal studies on the other will result in a synergistic effect that should allow the dissection of this complex trait.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- natural sciences biological sciences genetics
- social sciences sociology demography mortality
- medical and health sciences clinical medicine cardiology cardiovascular diseases arteriosclerosis
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Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
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Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
75634 PARIS
France
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.