Objective
Due to the systematic sequencing projects, the gap between the number of available protein sequences and structures increases, and the need for developing global proteomic programs becomes crucial. In this context, the prediction of new folds from scratch and the identification of characteristic folding fragments are necessary steps towards rational protein engineering and the elucidation of diseases related to misfolded structures. All the groups involved develop in silicon methods for determining protein structural subunits likely to correspond to key elements in the folding process. Our objective is to combine the expertise of the different groups and to transfer ideas and results in view of improving the efficiency of the individual approaches and establishing a synergetic prediction scheme of protein structure from sequence and conversely.
Funding Scheme
CON - Coordination of research actionsCoordinator
75252 Paris
France
Participants (7)
11855 Athens
91405 Orsay
102209 Heidelberg
91405 Orsay
1050 Bruxelles
31905 Haifa
Manchester
