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Content archived on 2024-05-24

Virus-induced gene silencing : unravelling the basis of a mechanism and its exploitation for the analysis of a multitude of individual gene functions in plants (VIS)

Objective

The objective of the proposal is to produce a detailed description of the molecular mechanisms underlying different stages of virus-induced gene silencing (VIGS) in plant cells. VIGS is a recently discovered sequence - specific RNA degradation mechanism in plants, that has a huge potential for the functional analysis of individual genes on the genome-wide scale, provided that its general principles are better understood. We plan to investigate the following aspects of VIGS: i) viral features detected by the plant^TMs surveillance mechanism; ii) suppressors of VIGS; iii ) host factors required for VIGS; v) role of DNA methylation in VIGS . The fulfilment of the project should pave the path for the construction of generally applicable efficient VIGS vectors for the functional analysis of multitude of plant genes.

Fields of science (EuroSciVoc)

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Topic(s)

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Call for proposal

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Funding Scheme

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CSC - Cost-sharing contracts

Coordinator

NATIONAL INSTITUTE OF CHEMICAL PHYSICS AND BIOPHYSICS
EU contribution
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Address
23,Akademia Tee 23
12618 TALLINN
Estonia

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Total cost

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Participants (7)

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