Objective While the role of classical neurotransmitters in neuronal communication is comparably well characterised, the actions of neuropeptides remained largely unknown. The objective of this proposal is to provide a complete understanding of the control of neuronal communication by the neuropeptide somatostatin through an elucidation of its antisecretory and antiproliferative actions. The functions of the individual somatostatin receptors will be unravelled in a multidisciplinary approach relying on the development and application of novel experimental tools and strategies. It will become clear how somatostatin signalling affects normal and abnormal brain function. Concepts will emerge regarding novel diagnostics and therapeutic strategies that can be used to treat patients from European populations that suffer from various brain disorders including neurodegenerative diseases, mental and affective disorders and aggressive brain tumours. Programme(s) FP5-LIFE QUALITY - Specific Programme for research, technological development and demonstration on "Quality of life and management of living resources", 1998-2002 Topic(s) 1.1.1.-9. - Neurosciences Call for proposal Data not available Funding Scheme CSC - Cost-sharing contracts Coordinator GERMAN INSTITUTE OF HUMAN NUTRITION Address Arthur-scheunert-allee 114-116 14558 Bergholz-rehbr cke Germany See on map EU contribution € 0,00 Participants (9) Sort alphabetically Sort by EU Contribution Expand all Collapse all INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE France EU contribution € 0,00 Address Rue de tolbiac, 101 75654 Paris See on map INSTITUTO NAZIONALE PER LA RICERCA SUL CANCRO Italy EU contribution € 0,00 Address Largo rosanna benzi 10 16132 Genova See on map MARIO NEGRI INSTITUTE FOR PHARMACOLOGICAL RESEARCH Italy EU contribution € 0,00 Address Via eritrea 62 20157 Milano See on map NOVARTIS PHARMA AG Switzerland EU contribution € 0,00 Address Lichtstrasse 35 Basel See on map OTTO VON GUERICKE UNIVERSITAET MAGDEBURG Germany EU contribution € 0,00 Address Leipzigstrasse 44 39120 Magdeburg See on map THE BABRAHAM INSTITUTE United Kingdom EU contribution € 0,00 Address Babraham hall Cambridge See on map Links Website Opens in new window UNIVERSITY OF CRETE Greece EU contribution € 0,00 Address Ampelokipoi 71110 Iraklion See on map UNIVERSITY OF HAMBURG Germany EU contribution € 0,00 Address Süderfeldstrasse 24 22529 Hamburg See on map Università degli Studi di Pisa Italy EU contribution € 0,00 Address Lungarno pacinotti 45 56100 Pisa See on map