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Content archived on 2024-05-18

Somatostatin and its receptors in brain function and dysfunction

Objective

While the role of classical neurotransmitters in neuronal communication is comparably well characterised, the actions of neuropeptides remained largely unknown. The objective of this proposal is to provide a complete understanding of the control of neuronal communication by the neuropeptide somatostatin through an elucidation of its antisecretory and antiproliferative actions. The functions of the individual somatostatin receptors will be unravelled in a multidisciplinary approach relying on the development and application of novel experimental tools and strategies. It will become clear how somatostatin signalling affects normal and abnormal brain function. Concepts will emerge regarding novel diagnostics and therapeutic strategies that can be used to treat patients from European populations that suffer from various brain disorders including neurodegenerative diseases, mental and affective disorders and aggressive brain tumours.

Topic(s)

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Call for proposal

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Funding Scheme

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CSC - Cost-sharing contracts

Coordinator

GERMAN INSTITUTE OF HUMAN NUTRITION
EU contribution
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Address
Arthur-Scheunert-Allee 114-116
14558 BERGHOLZ-REHBR CKE
Germany

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Total cost

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Participants (9)

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