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Neural stem cells and stem cell-based therapies

Objective

Therapies aimed at restoring neurological function by intracerebraltransplantation brings about ethical issues relative to the use of embryonic or foetal tissues. Human stem cells may represent a substitute for the use of such tissues In any grafting therapy. However, in order to use these cells successfully, it is necessary to fully understand the basic mechanisms that regulate there proliferate state, their mode of division and their differentiation potentials. Two major avenues will be pursued:
i) In vivo and inviter analysis of neural stem cell behaviour in simple organisms such asDrosophila melanogaster as well as in vertebrate nervous system;
ii) Design of cell replacement protocols in animal model systems for post-traumatic disorder.

Call for proposal

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Coordinator

CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
EU contribution
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Address
Rue Laurent Fries 1
67404 ILLKIRCH GRAFFENSTADEN
France

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Total cost
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Participants (5)