Neural stem cells and stem cell-based therapies

Objective

Therapies aimed at restoring neurological function by intracerebraltransplantation brings about ethical issues relative to the use of embryonic or foetal tissues. Human stem cells may represent a substitute for the use of such tissues In any grafting therapy. However, in order to use these cells successfully, it is necessary to fully understand the basic mechanisms that regulate there proliferate state, their mode of division and their differentiation potentials. Two major avenues will be pursued:
i) In vivo and inviter analysis of neural stem cell behaviour in simple organisms such asDrosophila melanogaster as well as in vertebrate nervous system;
ii) Design of cell replacement protocols in animal model systems for post-traumatic disorder.

Fields of science

• natural sciences › biological sciences › neurobiology
• medical and health sciences › medical biotechnology › cells technologies › stem cells

Programme(s)

• FP5-LIFE QUALITY - Specific Programme for research, technological development and demonstration on "Quality of life and management of living resources", 1998-2002

Topic(s)

• 1.1.1.-9. - Neurosciences

Call for proposal

Data not available

Funding Scheme

CSC - Cost-sharing contracts

Coordinator

CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE

Address

Rue Laurent Fries 1
67404 Illkirch Graffenstaden
France

Participants (5)

FONDAZIONE CENTRO SAN RAFFAELE DEL MONTE TABOR - ISTITUTO DI RICOVERO E CURA A CARATTERE SCIENTIFICO

Italy

Address

Via Olgettina 58
20132 Milano

JOHANNES GUTENBERG UNIVERSITAET MAINZ

Germany

Address

Joh.-joachim-becher-weg 32
55128 Mainz

KING'S COLLEGE LONDON

United Kingdom

Address

De Crespigny Park
W8 7AH London

UNIVERSITY COLLEGE LONDON

United Kingdom

Address

The Cruciform Building, Gower Street
WC1E 6BT London

UNIVERSITY OF UMEAA

Sweden

Address

Universitetsomraadet
901 87 Umeaa