Objective
A molecular explanation of how the vertebrate eye is built is the goal of this proposal. This is broken into three stages, the formation of the eye anlagen, the subdivision of the optic vesicle into the retina, pigment epithelium, and optics talk, and the generation of various neuronal cell types in the retina. The experiments here take advantage of modern molecular genetic analysis in four powerful vertebrate species to elucidate the roles the key genes involved in these processes and to identify new genes. Much of the work is focused on understanding the genetic and cellular interactions, the interplay of signalling molecules and transcription factors, extrinsic and intrinsic components of the genetic network of eye development. The recent discovery of retinal stem cells in vertebrates stimulates the last part of this proposal, a detailed characterisation of these cells using the knowledge gained from the investigation into eye development.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- medical and health sciences clinical medicine ophthalmology
- medical and health sciences medical biotechnology cells technologies stem cells
- natural sciences physical sciences optics
You need to log in or register to use this function
Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Data not available
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
CB2 3DY Cambridge
United Kingdom
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.