Objective
After cardiovascular disease and cancer, stroke and other hypoxia-related diseases are the third most common causes of death in many industrialised countries. In Europe, they represent the most important cause of morbidity and long-term disability imposing an enormous economic burden. The brain's response to hypoxia and ischemia, which helps determine the clinical outcome, is a complex pattern of events including the synthesis of neuroprotective proteins. These proteins will help to counteract the adverse effects of hypoxia or ischemia by increasing anaerobic metabolism, tissue vascularity and O2 delivery or by the elimination of toxic compounds. Neuroglobin is an O2-binding protein suggested to enhance the O2 supply of the brain. Its significance in brain metabolism in general and during hypoxia or ischemia is unknown. We propose to study neuroglobin in normal and pathologic conditions in order to elucidate its role in the survival of the neuron under hypoxic and ischemic conditions.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- natural sciences biological sciences biochemistry biomolecules proteins
- medical and health sciences clinical medicine cardiology cardiovascular diseases
- medical and health sciences clinical medicine oncology
- medical and health sciences basic medicine neurology stroke
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Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
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Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
2610 WILRIJK (ANTWERPEN)
Belgium
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.