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Content archived on 2024-05-24

A bio-active cochlear implant for severe deafness

Objective

A cochlear implant (CI) is a neuro-prosthesis for severe deafness. Our main objective is to pharmacologically treat the auditory nerve after CI, to protect the nerve from implantation trauma and to re-grow its peripheral processes. This treatment should improve speech understanding, enhancing the life quality of the patient. Animal studies, and studies on human tissue samples, will be performed to determine the efficacy of neurotrophins and antioxidants in preserving the auditory nerve following deafness. Delivery systems will also designed to supply drugs at the time of CI. Safety, effectiveness and dosage will be investigated, leading eventually to the first human trials of NTF in the inner ear. The outcomes of the research will have implications for the pharmacological treatment of hearing loss, for the use of NTF to prevent neural degeneration in CNS and for other neuroprostheses.

Topic(s)

Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.

Call for proposal

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Funding Scheme

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CSC - Cost-sharing contracts

Coordinator

UNIVERSITY OF TAMPERE
EU contribution
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Address
4,Medisiinarinkatu 3
33014 TAMPERE
Finland

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Total cost

The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.

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Participants (8)

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