Identification and characterization of factors involved in cyp3a4 inter-individual variability

Objective

Cytochrome P450 3A4 bio transforms many xenobiotics in human liver and has a highly variable expression. Identification of the genetic factors underling this variability is a key step in the prevention of fatal adverse drug reactions and carcinogen sis.

Programme(s)

• FP5-LIFE QUALITY - Specific Programme for research, technological development and demonstration on "Quality of life and management of living resources", 1998-2002

Topic(s)

• 1.1.1.-11. - Research relating to the persons with disabilities

Funding Scheme

RGI - Research grants (individual fellowships)

Coordinator

KAROLINSKA INSTITUTE

Address

Nobels Vaeg, 13
171 77 Stockholm
Sweden