Optimisation of typing policies for european marrow donors registries: socio-economic evaluation of molecular techniques and recruitment strategies

Objective

Although 6 million potential donors are registered worldwide, finding a donor compatible for allogeneic stern cell graft is hard because of HLA polymorphism. MADO (Marrow Donors) aims at evaluating optimisation of Registries in Europe by increasing the proportion of donors with rare HLA types to reduce inequality of patients in a cost/effective way. The main concept is an evolving filter to screen potential donors at low cost before full HLA typing for the likely presence of frequent types, using new markers and techniques. Organisational scenarios will then be designed. MADO involves 9 WP over 2 years and 12 partners in EU countries: 4 European Registries, sociologists, economists, public health unit, immunogenetics/molecular laboratories, bioinformatics, industry.

Programme(s)

• FP5-LIFE QUALITY - Specific Programme for research, technological development and demonstration on "Quality of life and management of living resources", 1998-2002

Topic(s)

• 1.1.1.-13. - Socio-economic aspects of life sciences and technologies

Call for proposal

Data not available

Funding Scheme

CSC - Cost-sharing contracts

Coordinator

INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE

Address

Alltes Jules Guesde 37 Facultt De Mtdtcine Purpan
37073 Toulouse
France

 

Participants (12)

ADVANCED BIOTECHNOLOGY CENTRE

Italy

Address

Largo Rosanna Benzi 10
16132 Genova

 

CONSORTIUM NATIONAL DE RECHERCHE EN GÉNOMIQUE

France

Address

Rue Gaston Cremieux, 2
91057 Evry

 

GROUPE GREFFE DE MOELLE - FRANCE - TRANSPLANT

France

Address

H(pital Saint Louis, Place Du Dr Fournier 2
75462 Paris

 

INTERNATIONAL GENETIC TECHNOLOGIES

France

Address

94654 Rungis

 

ITALIAN BONE MARROW DONOR REGISTRY

Italy

Address

Via Volta 19/5
16128 Genova

 

LEIDEN UNIVERSITY

Netherlands

Address

2,Albinusdreef 2
2300 RC Leiden

 

NATIONAL MEDICAL CENTER

Hungary

Address

Szabolcs U. 33-35
1135 Budapest

 

SEMMELWEIS UNIVERSITY

Hungary

Address

Uelloei-ut 26
1081 Budapest

 

STICHTING EUROPDONOR FOUNDATION

Netherlands

Address

Albinusdreef 2 (P/a Lumc E3 Q)
2333 ZA Leiden

 

THE ANTHONY NOLAN BONE MARROW TRUST

United Kingdom

Address

Pond Street, Royal Free Hospital
NW3 2QG London

 

UNIVERSIT DE TOULOUSE II - 'LE MIRAIL '

France

Address

Alltes Antonio Machado 5
31058 Toulouse

 

UNIVERSITE DE TOULOUSE 1, SCIENCES SOCIALES

France

Address

Allte De Brienne 21 Manufacture Des Tabacs Batimen
3100 Toulouse