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Optimisation of typing policies for european marrow donors registries: socio-economic evaluation of molecular techniques and recruitment strategies

Objective

Although 6 million potential donors are registered worldwide, finding a donor compatible for allogeneic stern cell graft is hard because of HLA polymorphism. MADO (Marrow Donors) aims at evaluating optimisation of Registries in Europe by increasing the proportion of donors with rare HLA types to reduce inequality of patients in a cost/effective way. The main concept is an evolving filter to screen potential donors at low cost before full HLA typing for the likely presence of frequent types, using new markers and techniques. Organisational scenarios will then be designed. MADO involves 9 WP over 2 years and 12 partners in EU countries: 4 European Registries, sociologists, economists, public health unit, immunogenetics/molecular laboratories, bioinformatics, industry.

Call for proposal

Data not available

Coordinator

INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE
Address
Alltes Jules Guesde 37 Facultt De Mtdtcine Purpan
37073 Toulouse
France
 

Participants (12)

ADVANCED BIOTECHNOLOGY CENTRE
Italy
Address
Largo Rosanna Benzi 10
16132 Genova
 
CONSORTIUM NATIONAL DE RECHERCHE EN GÉNOMIQUE
France
Address
Rue Gaston Cremieux, 2
91057 Evry
 
GROUPE GREFFE DE MOELLE - FRANCE - TRANSPLANT
France
Address
H(pital Saint Louis, Place Du Dr Fournier 2
75462 Paris
 
INTERNATIONAL GENETIC TECHNOLOGIES
France
Address

94654 Rungis
 
ITALIAN BONE MARROW DONOR REGISTRY
Italy
Address
Via Volta 19/5
16128 Genova
 
LEIDEN UNIVERSITY
Netherlands
Address
2,Albinusdreef 2
2300 RC Leiden
 
NATIONAL MEDICAL CENTER
Hungary
Address
Szabolcs U. 33-35
1135 Budapest
 
SEMMELWEIS UNIVERSITY
Hungary
Address
Uelloei-ut 26
1081 Budapest
 
STICHTING EUROPDONOR FOUNDATION
Netherlands
Address
Albinusdreef 2 (P/a Lumc E3 Q)
2333 ZA Leiden
 
THE ANTHONY NOLAN BONE MARROW TRUST
United Kingdom
Address
Pond Street, Royal Free Hospital
NW3 2QG London
 
UNIVERSIT DE TOULOUSE II - 'LE MIRAIL '
France
Address
Alltes Antonio Machado 5
31058 Toulouse
 
UNIVERSITE DE TOULOUSE 1, SCIENCES SOCIALES
France
Address
Allte De Brienne 21 Manufacture Des Tabacs Batimen
3100 Toulouse