Stable isotope applications to monitor starch digestion and fermentation for the development of functional foods.

Objective

The aim of this project is to characterise the "metabolic quality" of carbohydrates, with the main focus on starch. With 13C-stable isotope techniques, 13C-glucose response to various 13C-starch sources will be studied, including functions that could modulate this response such as gastric emptying / intestinal transit time and digestion rates. These functions will be manipulated by addition of rat, protein, dietary fibre and enzyme inhibitors in order to optimise the glycemic response. Fermentation of 13C-starch in man will be characterised by measuring small intestinal bioavailability, 13C-short chain fatty acid production and bacterial flora. This project will lead to a rationale for the development of breakfast food / biscuits with the target groups healthy people, diabetic patients and people at risk to diabetes and obesity.

Programme(s)

• FP5-LIFE QUALITY - Specific Programme for research, technological development and demonstration on "Quality of life and management of living resources", 1998-2002

Topic(s)

• 1.1.1.-1. - Key action Food, Nutrition and Health

Funding Scheme

CSC - Cost-sharing contracts

Coordinator

LUND UNIVERSITY

Address

60,Getingevaegen 60
221 00 Lund
Sweden

Participants (5)

CENTRE DE RECHERCHE EN NUTRITION HUMAINE DE LYON

France

Address

Place D'arsonval
69437 Lyon

GROUPE DANONE

France

Address

7,Rue De Tthtran 7
75381 Paris

HUMAN NUTRITION RESEARCH CENTRE OF NANTES

France

Address

Allee De L'ile Gloriette 5, Hotel Dieu
44093 Nantes

KATHOLIEKE UNIVERSITEIT LEUVEN

Belgium

Address

Herestraat 49
3000 Louvain / Leuven

UNIVERSITY OF GLASGOW

United Kingdom

Address

Rankine Avenue
G75 0QF Glasgow