The aim of this project is to characterise the "metabolic quality" of carbohydrates, with the main focus on starch. With 13C-stable isotope techniques, 13C-glucose response to various 13C-starch sources will be studied, including functions that could modulate this response such as gastric emptying / intestinal transit time and digestion rates. These functions will be manipulated by addition of rat, protein, dietary fibre and enzyme inhibitors in order to optimise the glycemic response. Fermentation of 13C-starch in man will be characterised by measuring small intestinal bioavailability, 13C-short chain fatty acid production and bacterial flora. This project will lead to a rationale for the development of breakfast food / biscuits with the target groups healthy people, diabetic patients and people at risk to diabetes and obesity.
Funding SchemeCSC - Cost-sharing contracts
3000 Louvain / Leuven
G75 0QF Glasgow